Normal Phase Diol SPE Cartridge

Description of Diol SPE Cartridge

Diol SPE cartridge weak anion exchange, the diol-based filler has similar silica gel retention and less acidity, carbon chain provides additional hydrophobic interaction, so it can be used as a normal phase or reverse phase absorber, extraction extracting polar compounds.

Diol is a medium-polarity adsorbent that binds polar bonded phase diol groups (-Si(CH₂)₃OCH₂CH(OH)CH₂OH) on a silica gel matrix.

Diol is similar to unbonded silica gel and tends to have strong hydrogen bonding. It is often used to extract polar samples from non-polar solutions.

If a silica gel cartridge is used, the acidity of the silica gel leads to the retention of alkaline impurities and can be replaced with a Diol SPE cartridge.

Features of Diol SPE Cartridge

• Can replace silica gel cartridge and avoid interference with alkaline impurities;
• Positive phase or reversed phase retention by the solvent ratio.

Application

• Analysis of pigments, phenols, and phospholipids in vegetable oils;
• Detection of drugs and metabolites in biological matrices such as urine;
• Separation and purification of glycan mixture.

Technical Data

Ordering Information