Normal Phase Diol SPE Cartridges

Normal Phase Diol SPE Cartridges

Diol is a medium-polarity adsorbent that binds polar bonded phase diol groups (-Si(CH₂)₃OCH₂CH(OH)CH₂OH) on a silica gel matrix.
Diol is similar to unbonded silica gel and tends to have strong hydrogen bonding. It is often used to extract polar samples from non-polar solutions.
Diol SPE cartridge weak anion exchange, the diol-based filler has similar silica gel retention and less acidity, carbon chain provides additional hydrophobic interaction, so it can be used as a normal phase or reverse phase absorber, extraction electrode Sex compounds.

If a silica gel cartridge is used, the acidity of the silica gel leads to the retention of alkaline impurities and can be replaced with a Diol SPE cartridge.

Features of Diol SPE Cartridges

Can replace silica gel cartridge and avoid interference with alkaline impurities
Positive phase or reversed phase retention by the solvent ratio

Application of Diol SPE Cartridges

Analysis of pigments, phenols, and phospholipids in vegetable oils
Detection of drugs and metabolites in biological matrices such as urine
Separation and purification of glycan mixture

Technical Data

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