Function group: C8/Sulfonic acid group
Retention Mechanism: reversed phase/cation-exchange selectivity
Mixed Mode Octyl(C8)/SCX SPE Cartridges
Description
Mixed Mode C8/SCX SPE Cartridges

The functional group of the C8/SCX (octyl/sulfonic acid silica gel) filler consists of a proportionally bonded octyl and sulfonic acid group with dual retention: the octyl group provides a moderate hydrophobic effect and the sulfonic acid group provides a strong cation exchange.
For samples that are over-adsorbed by C18 and C8 SPE cartridges, and that the SCX retention is too strong to cause elution difficulties, the C8/SCX mixed mode extraction cartridge can be used.
Features of Mixed Mode C8/SCX SPE Cartridges
Medium retention capacity, solving the problem that individual target compounds are difficult to elute.
Suitable for processing complex matrix samples such as blood and urine
Parameters
Specific surface area: 510 m² / g
Average particle size: 40-75 μm
Average pore size: 70 Å
Applications
C8/SCX mixed mode cartridge, Integrates the advantages of two packings, can satisfy a wide range of application needs, including:
Detection of drugs and metabolites in biological fluids, such as acetaminophen
Detection of drug abuse

Technical Data
Specification | Maximum Sample Load | Volume | Minimum Elution Volume |
---|---|---|---|
50-100mg | 2.5mg-5mg | 1mL | 100-200μL |
100-200mg | 5mg-10mg | 3mL | 200-500μL |
200mg-1g | 10mg-50mg | 6mL | 500μL-6mL |
500mg-2g | 25mg-100mg | 12mL | 3mL-10mL |
Ordering Information
Item No. | Specification | Package (pcs/pk) |
---|---|---|
SLSPE301C8SCX | C8/SCX, 30mg/1mL | 100 |
SLSPE1001C8SCX | C8/SCX, 100mg/1mL | 100 |
SLSPE2003C8SCX | C8/SCX, 200mg/3mL | 50 |
SLSPE5003C8SCX | C8/SCX, 500mg/3mL | 50 |
SLSPE2006C8SCX | C8/SCX, 200mg/6mL | 30 |
SLSPE5006C8SCX | C8/SCX, 500mg/6mL | 30 |
SLSPE1K6C8SCX | C8/SCX, 1g/6mL | 30 |
SLSPE1K12C8SCX | C8/SCX, 1g/12mL | 20 |
SLSPE2K12C8SCX | C8/SCX, 2g/12mL | 20 |