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Mixed Mode Octyl(C8)/SCX SPE Cartridges

Function group: C8/Sulfonic acid group
Retention Mechanism: reversed phase/cation-exchange selectivity


Description of Mixed Mode C8/SCX SPE Cartridges

The functional group of the C8/SCX (octyl/sulfonic acid silica gel) filler consists of a proportionally bonded octyl and sulfonic acid group with dual retention: the octyl group provides a moderate hydrophobic effect and the sulfonic acid group provides a strong cation exchange.
For samples that are over-adsorbed by C18 and C8, and that the SCX retention is too strong to cause elution difficulties, the C8/SCX mixed mode extraction cartridge can be used.

Features of Mixed Mode C8/SCX SPE Cartridges

Medium retention capacity, solving the problem that individual target compounds are difficult to elute.
Suitable for processing complex matrix samples such as blood and urine


Specific surface area: 510 m² / g
Average particle size: 40-75 μm
Average pore size: 70 Å


C8/SCX mixed mode cartridge, Integrates the advantages of two packing, can satisfy a wide range of application needs, including:
Detection of drugs and metabolites in biological fluids, such as acetaminophen
Detection of drug abuse


Mixed Mode C8/SCX SPE Cartridges

Technical Data

Specification Maximum Sample Load Volume Minimum Elution Volume
50-100mg 2.5mg-5mg 1mL 100-200μL
100-200mg 5mg-10mg 3mL 200-500μL
200mg-1g 10mg-50mg 6mL 500μL-6mL
500mg-2g 25mg-100mg 12mL 3mL-10mL

Ordering Information

Item   No.  Specification Package (pcs/pk)
SLSPE301C8SCX C8/SCX, 30mg/1mL 100
SLSPE1001C8SCX C8/SCX, 100mg/1mL 100
SLSPE2003C8SCX C8/SCX, 200mg/3mL 50
SLSPE5003C8SCX C8/SCX, 500mg/3mL 50
SLSPE2006C8SCX C8/SCX, 200mg/6mL 30
SLSPE5006C8SCX C8/SCX, 500mg/6mL 30
SLSPE1K6C8SCX C8/SCX, 1g/6mL 30
SLSPE1K12C8SCX C8/SCX, 1g/12mL 20
SLSPE2K12C8SCX C8/SCX, 2g/12mL 20
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