:Home/SPE Cartridges/Ion-Exchange PSA SPE Cartridges

Ion-Exchange PSA SPE Cartridges

Mechanism of action: PSA
Particle size: 50-75μm
Average pore size: 100 Å


Description of Ion-Exchange PSA (ethylenediamine-N-propyl) SPE Cartridges

PSA is a polar adsorbent bonded to N-propylethylenediamine (-Si(CH2)3NH(CH2)2NH2) on a high-purity silica gel matrix. It has no terminal group capping. The main retention mechanism is weak anion exchange (water solubility). Polar organic matrix (non-polar organic matrix), and chelation.

Similar to the aminopropyl bond phase of NH2, but PSA has two amino groups (primary and secondary amines), and the two amino groups have higher pKa values (10.1 and 10.9, respectively), so PSA has higher ion exchange capacity and stronger ion exchange capacity; at the same time, the bonded phase of PSA as bidentate ligands, which can produce chelation, a chemical reaction useful in metal ion extraction; and because its carbon loading is higher than NH2 adsorbent. Therefore, the polarity of PSA is weaker than that of NH2, and the polar compound which is too strongly retained on the NH2 pillar can be replaced by a PSA cartridge.

Advantages of Ion-Exchange PSA (ethylenediamine-N-propyl) SPE Cartridges

High-capacity design ensures that the volume of the small bed can carry a relatively large number of samples while ensuring good extraction results.
Larger exchange capacity than NH2
Effectively remove multiple interference components from food
High purity, high controllable specific surface area to ensure stable extraction efficiency
No blank background interference at all
Can be used for SPE combined with GC/MS and LC/MS detection technology


carbon content: 8%
Specific surface area: 500 m²/g
Particle size: 50-75 μm
Average pore size: 100 Å

Applications Fields:

Soil; water; body fluids (plasma/urine, etc.); food; petroleum
Typical application:
PSA packing allows you to load SPE cartridges yourself to meet a wide range of application needs, including:
Detection of sedatives in body fluids.
Removal of fatty acids (such as oleic acid, palmitic acid, linoleic acid) that affect the detection of food matrices, organic acids, partial pigments, metal ions, carbohydrate interferences, etc.

PSA SPE Cartridge

PSA SPE Cartridges

Technical Data

Specification Maximum Sample Load Volume Minimum Elution Volume
50-100mg 2.5mg-5mg 1mL 100-200μL
100-200mg 5mg-10mg 3mL 200-500μL
200mg-1g 10mg-50mg 6mL 500μL-6mL
500mg-2g 25mg-100mg 12mL 3mL-10mL

Ordering Information

Item   No.  Specification Package (pcs/pk)
SLSPE1001PSA PSA, 50-75μm, 100Å, 100mg/1mL 100
SLSPE2003PSA PSA, 50-75μm, 100Å, 200mg/3mL 50
SLSPE5003PSA PSA, 50-75μm, 100Å, 500mg/3mL 50
SLSPE5006PSA PSA, 50-75μm, 100Å, 500mg/6mL 30
SLSPE1K6PSA PSA, 50-75μm, 100Å, 1g/6mL 30
SLSPE1K12PSA PSA, 50-75μm, 100Å, 1g/12mL 20
SLSPE2K12PSA PSA, 50-75μm, 100Å, 2g/12mL 20
SLSPE502PSA PSA, 50-75μm, 100Å, 50mg/2mL/w 96w
SLSPE1002PSA PSA, 50-75μm, 100Å, 100mg/2mL/w 96w
SLSPE100KPSA PSA, 50-75μm, 100Å, 100g bottle
Enter your email address and our sales staff will contact you as soon as possible.