Ion-Exchange PSA SPE Cartridge

PSA SPE Cartridges

PSA is a polar adsorbent bonded to N-propylethylenediamine (-Si(CH₂)₃NH(CH₂)₂NH₂) on a high-purity silica gel matrix. It has no terminal group capping. The main retention mechanism is weak anion exchange (water solubility). Polar organic matrix (non-polar organic matrix), and chelation.

Similar to the aminopropyl bond phase of the NH2 SPE cartridge, but the PSA cartridge has two amino groups (primary and secondary amines), and the two amino groups have higher pKa values (10.1 and 10.9, respectively), so the PSA SPE cartridge has a higher ion exchange capacity and stronger ion exchange capacity; at the same time, the bonded phase of PSA as bidentate ligands, which can produce chelation, a chemical reaction useful in metal ion extraction; and because its carbon loading is higher than NH2 adsorbent. Therefore, the polarity of PSA is weaker than that of NH2, and the polar compound which is too strongly retained on the NH2 pillar can be replaced by a PSA cartridge.

Advantages of Ion-Exchange PSA (ethylenediamine-N-propyl) SPE Cartridge

• High-capacity design ensures that the volume of the small bed can carry a relatively large number of samples while ensuring good extraction results;
• Larger exchange capacity than NH2;
• Effectively remove multiple interference components from food;
• High purity, high controllable specific surface area to ensure stable extraction efficiency;
• No blank background interference at all;
• Can be used for SPE combined with GC/MS and LC/MS detection technology.

Parameters of PSA SPE Cartridge

• carbon content: 8%;
• Specific surface area: 500 m²/g;
• Particle size: 50-75 μm;
• Average pore size: 100 Å.

Applications Fields

• Soil; water; body fluids (plasma/urine, etc.); food; petroleum
• Typical application: PSA packing allows you to load SPE cartridges yourself to meet a wide range of application needs, including: Detection of sedatives in body fluids.
• Removal of fatty acids (such as oleic acid, palmitic acid, linoleic acid) that affect the detection of food matrices, organic acids, partial pigments, metal ions, carbohydrate interferences, etc.

Technical Data

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