Polymeric MCX SPE Cartridges

Polymeric MCX SPE cartridges are used to extract strongly alkaline compounds. MCX is a mixed strong cation exchange adsorbent obtained by bonding sulfonic acid groups on highly crosslinked PS/DVB surface. It has both reverse phase and cationic exchange retentive properties and good retention ability for alkaline compounds. You also can choose Mixed Mode Octyl(C8)/SCX SPE Cartridge, Reversed Phase C18 SPE Cartridge, SAX SPE Cartridges, Normal Phase PR Grade Florisil SPE Cartridges and other SPE Cartridges using.

Key Features

  1. Polymeric Sorbent:
    • The sorbent in MCX SPE cartridges is typically a polymeric material with functional groups that can facilitate both ion-exchange interactions (for cations) and hydrophobic interactions.
  2. Mixed-Mode Functionality:
    • The mixed-mode functionality allows for multiple interactions between the sorbent and analytes, providing enhanced selectivity in the extraction process.
  3. Cation Exchange Capacity:
    • The cation exchange capacity of the sorbent enables the selective retention of positively charged analytes. This is particularly useful for extracting and purifying cationic species from complex samples.
  4. Hydrophobic Interaction:
    • The hydrophobic interactions contribute to the retention of non-polar or weakly polar analytes, adding versatility to the extraction process.
  5. Versatility:
    • MCX SPE cartridges are versatile and suitable for a wide range of applications, including the extraction of small organic molecules, pharmaceuticals, pesticides, and other cationic analytes.
  6. Compatibility:
    • These cartridges are compatible with a variety of sample matrices, including biological fluids, environmental samples, and complex mixtures.
  7. Optimized Bed Chemistry:
    • The bed chemistry of the sorbent is optimized for efficient extraction and recovery of analytes while minimizing unwanted matrix interferences.
  8. Available Formats:
    • MCX SPE cartridges are available in various formats, including traditional cartridges, 96-well plates, and other configurations, to suit different sample volumes and throughput requirements.

Characteristics of polymeric MCX SPE cartridges

1. High retention of basic compounds;
2. Large specific surface area and high ion exchange capacity;
3. Wide pH tolerance range (pH 1-14), stable in organic solution;
4. No blank background interference;
5. Stable quality and good reproducibility;
6. It is easy to operate and can achieve an excellent flow rate.

Parameter of polymeric MCX SPE cartridges

1. Specific surface area: 600 m2/g;
2. Average particle size: 40μm;
3. Average aperture: 300 Å.

Application of polymeric MCX SPE cartridges

1. Detect pesticide and veterinary drug residues in food, such as clenbuterol and malachite green;
2. Analyze drugs and their metabolites in the biological matrix, such as anti-estrogen drugs and benzodiazepines.
3. Polymeric MCX SPE cartridges are especially suitable for milk analysis of melamine in food and feed.