Common terminology for solid phase extraction (part 2)

Polar Interaction: The interaction between a polar functional group on a target compound and a polar functional group on the adsorbent. This force is better reflected in a weakly polar or non-polar solvent environment. ;

Ion Interaction: the Coulomb force between an ionic functional group on an ionic target compound and an oppositely charged functional group on the adsorbent;

Secondary Interaction: For reversed-phase silica-bonded adsorbents, the residual silanol groups on the surface of the particles interact polarly with polar compounds, and some of the silanol groups dissociate from the basic compounds. Role, these forces are secondary to non-polar interactions and are therefore referred to as secondary interactions. Secondary interactions are undesirable for reversed phase silica adsorbents and can usually be eliminated by endcaping;

Activation: Also known as solvation, adding a suitable solvent to expand the functional groups on the adsorbent and removing possible interferences on the adsorbent. For reversed-phase adsorbents, medium-polar solvents (such as methanol) are often used. Phase adsorbents often use weakly polar or non-polar solvents such as hexane;