Applications and Advantages of QuEChERs

QuEChERs is considered to be a multi-species and multi-residue detection method for agricultural residues analysis in a matrix with high moisture content with the advantages of economy, speed, sensitivity, and enough precision, which makes the detection of high water content food more simple and economical.

Solvents of QuEChERs

The preferred solvent is acetonitrile because it extracts the widest range of organic matter without simultaneously extracting large amounts of lipophilic material. Although other solvents may be used depending on the residual required for extraction. However, due to the high compatibility of acetonitrile with GC/MS and LC/MS, the interference can be minimized.

Advantages of QuEChERs

Because the various chemical properties of samples may conflict with the nature of agricultural residues, the analysis of pesticide residues in food and environmental samples is prone to some separation problems. Moreover, a large amount of chlorophyll, lipids, and other compounds may exist in the complex sample matrix, which will seriously interfere with the sample analysis. QuEChERs can reduce these problems.
There are three versions of QuEChERs used in the United States.
1. Sodium chloride was used to enhance the extraction effect.
2. Use sodium acetate instead of sodium chloride as a buffer.
3. Double-layer extraction column.